When we set the Q1(ALB < 3.6 g/dL) group as a reference, the higher value or proportion of Hb, eGFR, CKD stage 2–3, and etiology of CKD as nephrosclerosis were detected in the Q4 (Hb ≥ 4.3 g/dL) group, while the lower value and proportion of age, UCPR, SBP, urinary occult blood, use of diuretics, Scr, hypertension, diabetes, use of CCB, history of CVD, CKD stage 4–5, and etiology of CKD as diabetic nephropathy were observed. The gene discussed is GSTM1; the disease is diabetic kidney disease.