To resemble the insufficient, but not deleted, status of YTHDC1 in colitis, we crossed Ythdc1f/+ mice with LysM‐Cre mice to generate Ythdc1flox/+;Lysm‐Cre mice (hereafter referred to as mYthdc1+/−) with deficient YTHDC1 in macrophages (Figure S3h, Supporting Information). This evidence concerns the gene YTHDC1 and colitis.