SMARCA4 and colorectal carcinoma: To investigate the potential effects of SMARCA4 wild-type (WT), R1157W, R1157Q, or R1243Q mutants on the growth of CRC cells, we transfected SMARCA4-WT, -R1157W, -R1157Q, or -R1243Q mutant overexpression plasmids into HCT116 and SW620 CRC cells.