In addition, the analysis of pathological information from these clinical samples showed that the SMARCA4-R1157W (SMARCA4R1157W) mutation was associated with higher-grade CRC (Supplementary Table 1), suggesting greater malignancy in patients with SMARCA4R1157W mutation than in patients with wild-type SMARCA4. The gene discussed is SMARCA4; the disease is colorectal carcinoma.