To identify the key genetic mutations of SWI/SNF complex subunits associated with CRC, we analyzed genetic alterations of SMARCA4 (BRG1), SMARCA2 (BRM), SMARCB1 (BAF47 or SNF5), SMARCC1 (BAF155), SMARCC2 (BAF170), SMARCE1 (BAF57), ARID1A (BAF250A), ARID1B (BAF250B), and other common oncogenes (MLH1, CDKN2A, and EGFR) in CRC from the cBioPortal database30. The gene discussed is CDKN2A; the disease is colorectal carcinoma.