Underlying conditions, beside SCD, were identified in seven patients (63.6%) in the positive group, being one case of overweight, one of epilepsy, one of epilepsy and insulin resistance, one of bipolar disease, one of short stature undergoing growth hormone treatment, one of asthma and pyelocaliceal dilation, and one of asthma and left ventricular dilation. The gene discussed is GH1; the disease is Schnyder corneal dystrophy.