In addition, expression levels of adhesion molecules and chemokine receptors CD11a (integrin-α L; LFA-1), CD11b (integrin-α M; Mac-1), CD11c (integrin-α X), CD18 (integrin β-2), CD29 (integrin β-1), CD49d (integrin β-4), CD162 (P-selectin receptor), and CX3CR1 (CX3CL1 receptor) were analyzed in patients with obesity and compared with healthy control subjects using flow cytometry. The gene discussed is ITGAL; the disease is obesity due to melanocortin 4 receptor deficiency.