CXCR4 and neoplasm: Consistent with the above scRNA-Seq analyses, the Yap1;TazDKO mice showed a significantly lower relative amount of tiNeus (Cd11b+Ly6G+Ly6Clo) (Figs. 5J and S5C), but a significantly higher relative amount of tumor-infiltrated preNeus (c-kit+CXCR4+) (Fig. S5D) than did the wild-type mice.