CXCR4 and neoplasm: From the flow cytometric analysis, we observed preNeus (CD11b+Gr1+CXCR4+c-Kit+) in tumor-bearing mice showing a gradual upregulation of c-Kit and a subsequent bifurcation branch of c-Kit− neutrophils into CD101− and CD101+ cells, corresponding to the previously characterized immNeus and mNeus, respectively (Fig. S2A) (Evrard et al., 2018b).