NPM1 and acute myeloid leukemia: High classification performance with F1 scores of 0.75±0.06 (NPM1), 0.69±0.09 (CBFB::MYH11), and 0.75±0.15 (RUNX1::RUNX1T1) showed that single-cell blood smear morphology can be used to automatically discriminate between AML genetic subtypes, which in turn indicated morpho-genetic correlations learned by our model.