CCL2 and obesity due to melanocortin 4 receptor deficiency: Compared with children with normal body weight, those with overweight/obesity and MetS had significantly higher BMI, systolic blood pressure (SBP), diastolic blood pressure (DBP), TGL, and MCP-1, and significantly lower HDL-C and TGL/HDL-C ratio (4.51(3.15); p<0.0001).