TP53 and malignant colon neoplasm: Similarly, hsa-miR-30e-5p is a novel effector of p53-induced suppression of migration, invasion, and metastasis in colon cancer.30 The expression of hsa-miR-30e-5p decreases by 1.79-fold after ST treatment in H508 cells while decreases 2.9-fold in SNU-C4 cells.