To identify the predictive value of BDH1 for lymph node metastases and distant metastases of lung cancer, we analysed the exon sequencing data of 188 patients with lung cancer from TCGA and obtained three genes that were associated with lymph node metastases and cell migration, with a crude p ˂ 0.05, through multivariate logistic regression. The gene discussed is BDH1; the disease is metastatic malignant neoplasm in the lymph nodes.