MKI67 and neoplasm: Although BLU9931 resulted in slightly lower mean tumor volumes in KPC/Hmga1 heterozygous implants in addition to decreased HMGA1, FGF15, and Ki-67 staining, and 2 of 3 CAF subtypes, the changes were modest, as tumor growth was markedly diminished by Hmga1 haploinsufficiency alone (Supplemental Figure 8, A–E).