GJA1 and myocardial infarction: As such, interfering with CT-CL interaction has the dual potential of preventing both the closure of Cx43 GJs and the opening of HCs, which offers an interesting opportunity to follow up on the disappointing outcome of the danegaptide study on myocardial infarction patients (45) with new candidate molecules based on RRNYRRNY and CyRP-71 “RXP”-type Cx43-binding peptides (88).