We found that COMMD10 expression levels were significantly higher in STAD tumor tissues than in paracancerous tissues through the TCGA database, and subsequently we analyzed the differences in mRNA expression levels of different cell lines and protein expression levels of cells and tissues, and found that COMMD10 expression was significantly higher in GC tumor tissues both at the transcriptional and translational levels. The gene discussed is COMMD10; the disease is gastric adenocarcinoma.