LINP1 and skin squamous cell carcinoma: Hierarchical Clustering Algorithm after z-score standardization processing of the original normalized expression of the top ten highest upregulated and downregulated LncRNAs in cSCC tumors showed that lncRNA in non-homologous end joining pathway 1 (LINP1) is ranked as the top first LncRNA and significantly higher-expressed in cSCC compared with normal skin tissues (Fig. 1A) [23].