APP and Alzheimer disease: In the current study, while there were no differences detected in the stratum radiatum, more astrocytes in the stratum lacunosum-moleculare were found to contain glycogen granules in the APP-PS1 mice compared to C57BL/6J control mice (Control 7.895 ± 4.433% of astrocytes vs AD 47.06 ± 8.689% of astrocytes, p = 0.0002).