Another dataset (GDC data portal) also shows the MUC16 expression is significantly upregulated in various metastases (individual metastases not available) (N = 40) as compared to primary breast tumors (N = 1334) (Additional file 3: Fig. S3C), indicating that the MUC16/HuR axis is associated with breast cancer metastasis. This evidence concerns the gene MUC16 and breast cancer.