GPX4 and neuroblastoma: A study found that when SH-SY5Y human neuroblastoma cells were treated with PQ (paraquat dichloride) and Fer-1 (a specific inhibitor of ferroptosis) together, Fer-1 could inhibit the production of lipid reactive oxygen species and ameliorate ferroptosis by upregulating the expression of GPX4 (glutathione peroxidase 4) and SLC7A11 (cystine/glutamate antiporter).