TNF and Parkinson disease: In addition, GSEA analysis of KEGG pathway uncovered some underlying pathways in PD (Table 1), such as autophagy, apoptosis, necroptosis, NOD-like receptor signaling pathway, TNF signaling pathway, ubiquitin mediated proteolysis, cellular senescence, mitophagy, Parkinson disease, alcoholic liver disease and neutrophil extracellular trap formation.