BC: Breast cancer; NAC: Neoadjuvant chemotherapy; pCR: Pathological complete response; IDC: Invasive ductal carcinoma; ER: Estrogen receptor; PR: Progesterone receptor; HER-2: Human epidermal growth factor receptor-2; CEA: Carcinoembryonic antigen; CA153: Carbohydrate antigen 153: WBC: White blood cell; Hb: Hemoglobin; PLT: Platelet; LYM: Lymphocyte; ALB: Albumin; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; SII: Systemic immune inflammation index. The gene discussed is CEACAM5; the disease is breast cancer.