ESR1 and neoplasm: The results showed that pCR was significantly correlated with tumor grade (P = 0.033), ER (P = 0.037), molecular classification (P = 0.046), therapy cycle (P = 0.039), WBC (P = 0.037), PLT (P = 0.038), LYM (P < 0.001), NLR (P < 0.001), PLR (P < 0.001), LMR (P = 0.001) and SII (P = 0.001) (Table 2).