TSPYL2 and cancer: We found data about TSPYL2 gene for 10953 cancer patients (Supplementary Fig. 5A), and we identified TSPYL2 mutations in 225 of them (2%), with missense mutations being the most represented (37,3%), followed by amplifications (27,1%), homodeletions (22,7%) and truncating mutations (10,2%) (Supplementary Fig. 5B).