PPP1R15B and Intellectual disability: PPP1R15B, a protein phosphatase that dephosphorylates eIF2α is associated with MODY (Abdulkarim et al. 2015, Kernohan et al. 2015) and two patients from a consanguineous family with homozygous missense mutation in PPP1R15B had juvenile onset diabetes, low height (Abdulkarim et al. 2015) and microcephaly, cerebral impairment, intellectual disability (Kernohan et al. 2015).