PPP1R15B, a protein phosphatase that dephosphorylates eIF2α is associated with MODY (Abdulkarim et al. 2015, Kernohan et al. 2015) and two patients from a consanguineous family with homozygous missense mutation in PPP1R15B had juvenile onset diabetes, low height (Abdulkarim et al. 2015) and microcephaly, cerebral impairment, intellectual disability (Kernohan et al. 2015). The gene discussed is PPP1R15B; the disease is MODY.