CORT and Hyperglycemia: Since STZ-pretreated CORT-treated (STZ+ CORT+) mice exhibited a hyperglycemia-related increase in water intake, they were provided water with half-concentration CORT solution throughout the study (Figure 5A), resulting in an equivalent intake of total CORT compared with vehicle-pretreated CORT-treated (STZ− CORT+) mice (Figure 5B).