CD8A and COVID-19: With respect to cell-mediated immunity, it is noteworthy that the N protein is far and away the dominant SARS-CoV-2 protein recognized by CD8+ T cells of COVID-19 convalescent patients, recognized by 57% of these patients, and among patients with SARS-CoV-2 responding CD8+ T cells, a median of 43% of their CD8+ T cells recognized N peptides (36).