To investigate the influence of different factors on anti-Spike RBD antibody levels after administration of inactivated SARS-CoV-2 vaccine, we examined the effects of age, gender, the brand of inactivated SARS-CoV-2 vaccine received (Sinovac CoronoVac or Sinopharm BBIBP-CorV), duration of post-vaccination interval, family history of cardiovascular diseases, and BMI. This evidence concerns the gene CHMP5 and cardiovascular disorder.