SMARCA1 and neoplasm: Thus, a biologically relevant dysregulation of the SWI/SNF complex could affect subclones of a given tumor, for example, by inactivating mutations of ARID1A,25 and may involve several members of the SWI/SNF complex making it difficult to unravel correlations with patient survival when SMARCA4 or SMARCE1 are explored individually: the expression of SMARCA4 or SMARCE1 did not correlate with patient survival.