AKT1 and intervertebral disk degenerative disorder: In addition, Luo et al.261found that compared with degenerative CEP stem cell‐derived exosomes (D‐exos), normal CEP stem cell‐derived exosomes (N‐exos) can inhibit TBHP‐induced NPCs apoptosis and delay the progression of IDD by activating autophagy mediated by PI3K/AKT pathway.