IL6 and Dysmenorrhea: However, in the etiological study of dysmenorrhea, it was found that the concentrations of some inflammatory factors, such as prostaglandin F2α (PGF2α), tumor necrosis factorα (TNF), interleukin 6 (IL-6), C-reactive protein (CRP), vascular endothelial growth factor (VEGF) were increased in the menstrual cycle of dysmenorrhea patients [1,[25], [26], [27]].