TNNI3 and pericardial effusion: Several abnormal findings were seen across all groups, including 1) reduction in LVEF, wall motion abnormalities, or new/worsening pericardial effusions in 18/26 patients (69%), 2) ECG abnormalities such as ischemic T wave changes, new conduction abnormality or new tachyarrhythmias in 20/26 patients (91%), 3) cardiac troponin I elevation in 16/24 patients (67%) and 4) inflammation including myositis or other major organ inflammation in 4/26 patients (15%).