This is consistent with other pre-clinical studies: Zhu et al. showed, in an LPS model of sepsis, that Ang-(1–7) reduced the levels of urea, creatinine, and cystatin C, with a similar reduction in the inflammatory cytokines tumor necrosis factor (TNF)-α, IL-1, and IL-6 in serum and kidney [15]. The gene discussed is CST3; the disease is Sepsis.