CXCL12 and Bloom syndrome: GEO datasets (GSE181508 and GSE47460) were analyzed, and we found that the expression level of SDF1 in the endothelial cells of mice with BLM-induced fibrosis was significantly upregulated compared to that in the control group (Fig. 6C), and SDF1 expression in IPF lungs and the endothelial cells of BLM-induced fibrotic mouse lungs was positively correlated with MMP19 expression (Fig. 6D).