For OS outcomes of glioma patients, a 9-gene signature was selected to construct the prognostic score using their regression coefficients: Riskscore = (0.8949)*FDX1 + (0.4902)*DLD + (0.0778)*DLAT + (-0.9324)*LIAS + (0.1132)*GLS + (0.903)*LIPT1 + (-0.1847)*MTF1 + (-0.2352)*PDHA1 + (-0.2045)*PDHB. Here, PDHA1 is linked to central nervous system cancer.