We observed that the KLRG1–CD127+ memory precursor population was substantially decreased by more than twofold among transferred LATG135D.OT-I.Rag1–/– CD8 T cells compared with transferred LAT wild-type cells in response to Lm-OVA infection (Fig. 6c,d and Extended Data Fig. 9d), whereas the short-lived KLRG1+CD127– effector cell population was consistently larger. Here, LAT is linked to infection.