This effect was increased to sevenfold, when von Willebrand factor (vWF) levels were increased.33Additionally, TFPI levels were generally higher in non-ST segment elevation myocardial infarction (NSTEMI) compared with ST-segment elevation myocardial infarction (STEMI) patients.34In another study, TFPI levels in hospitalized patients with acute coronary syndrome (ACS) were indicative for the severity of myocardial infarction (MI) but were not associated with mortality.35 This evidence concerns the gene TFPI and acute coronary syndrome.