SORT1 and metabolic syndrome: Moreover, polymorphism of the genomic region-rs646776 within the cadherin endothelial growth factor (EGF) LAG seven-pass G-type receptor 2 (CELSR2), proline/serine-rich coiled-coil 1 (PSRC1), and sortilin 1 (SORT1) gene cluster is related to dyslipidemia and atherosclerosis [7].