Post-infectious glomerulonephritis triggered by bacterial infections (such as group A streptococci and staphylococcus) often present as endocapillary proliferative glomerulonephritis, which is typically characterized by polyclonal Ig with intense granular C3 deposition along the capillary wall and subepithelial hump-like electron-dense deposits. The gene discussed is C3; the disease is proliferative glomerulonephritis.