Evidence shows that immunizations result in modulation of the response of production of IgA and IgG antibodies, as well as a response of inflammatory cells, particularly polymorphonuclear cells (PMNs) that are exuded into the lumen of the nasal cavity, where cells and antibodies are suggested to work together to prevent N. fowleri adhesion to the olfactory epithelium of the nasal cavity, which is a crucial step to avoid the infection (Carrasco-Yepez et al. 2014; Rojas-Hernández et al. 2004a). This evidence concerns the gene CD79A and infection.