Data in panels D–H show BM numbers from WT mice transplanted with 3×106 BCR-ABL-expressing B-ALL cells and treated with HEL-Ig or LTβR-Ig (150 μg/mouse) on day 0 and day 5; mice were analyzed on day 8 post ALL transplantation. This evidence concerns the gene LTBR and acute lymphoblastic leukemia.