Recently, Ozturk et al reported that a combined analysis of SWI and DWI could differentiate atypical glioblastoma from primary CNS lymphoma, including molecular criteria using scores relative to the contralateral hemisphere (rSWI): glioblastomas without the IDH1 mutation demonstrated a significantly lower rSWI value compared to glioblastomas with an IDH1 mutation and PCNSL.63 The gene discussed is IDH1; the disease is primary central nervous system lymphoma.