The cytotoxic response to these antigens is much weaker than the initial viral antigens but causes a persistent low‐level activation of autoreactive CD8+ T cells (Misko et al, 1999) as for example shown for Psoriasis, type I diabetes and recently for multiple sclerosis and age‐dependent neuronal degeneration (Valdimarsson et al, 2009; Campisi et al, 2022; Girdhar et al, 2022; Zhou et al, 2022). Here, CD8A is linked to psoriasis.