Meanwhile, in 10 cancer types (COAD, STAD, LUAD, BLCA, SKCM, CESC, BRCA, UCEC, SARC, PAAD), high-TMB cancers displayed significantly higher PD-L1 expression levels than low-TMB cancers (two-tailed Student’s t test, P < 0.1). Here, CD274 is linked to cancer.