Although IL-3-stimulated pDCs were described to preferentially drive allogenic T cell differentiation into Th2 cells, our data show that IL-3-treated pDCs were associated with higher levels of IFNγ upon viral stimulation, as observed after HSV infection (30), suggesting then that IL-3 functions during viral infection as an amplifier of TLR signalling as observed in systemic lupus erythematosus (32). The gene discussed is IFNG; the disease is viral infectious disease.