AFP and liver cancer: To further study the effect of AFP on the phagocytosis of macrophages, in this study, liver cancer-derived AFP(tAFP) was treated in THP-1- derived M1 cells and monocyte-derived macrophages from healthy donors, and the effect of tAFP on macrophages phagocytizing, the phagocytosis of THP-1-derived M1 and monocytes-derived macrophages was observed.