AFP and liver cancer: First, we observed the influence of tAFP in THP-1 derived M1-like macrophages phagocytizing polystyrene latex beads or liver cancer cells(HLE(non-AFP expressed line)), the results indicated that when treated with tAFP(final concentration 20μg/mL), the THP-1 derived M1-like macrophages phagocytized polystyrene latex beads or HLE cells was significantly decreased (Figures 7A, B).