In the human liver, the expression levels of Fmnl1 and Myh9 in the MMD system (CCR2/CD68/CD11c+ cells in humans) were also increased with collagen deposition, and the expression levels of Fmnl1 and Myh9 increased with aggravation of the liver fibrosis stage (all p<0.05, Figure 6 and Supplementary Figure 5). The gene discussed is ITGAX; the disease is Hepatic fibrosis.