The employed docking server illustrated significant binding of the constructed multiepitope vaccine at both TLR isotypes, TLR4 and TLR2, where these innate immunity receptors are highly reported for their important role within the host’s defense throughout infections by K. pneumonia (Wieland et al., 2011; Paczosa and Mecsas, 2016; Jeon et al., 2017; Dar et al., 2019; Allemailem, 2021). The gene discussed is TLR4; the disease is infection.