SRSF1 is upregulated in varies cancer type (Ghigna et al., 2005; Karni et al., 2007; de Miguel et al., 2014; Anczukow et al., 2015) and controls alternative splicing of many tumor-related genes, which affect cell apoptosis (Olsson and Zhivotovsky, 2011; Anczukow et al., 2012; Gautrey and Tyson-Capper, 2012), proliferation and migration (Ghigna et al., 2005) thereby promoting tumorigenesis and cancer development. This evidence concerns the gene SRSF1 and cancer.