The results presented the expression of CASP3, GPX4, GSDME, and PRKACA was increased, while the expression of AIM2, CASP1, CASP4, CASP5, CASP8, CASP9, ELANE, GSDMA, GSDMB, GSDMD, IL1B, IL6, IL18, NLRC4, NLRP1, NLRP2, NLRP3, NLRP6, NOD1, NOD2, PJVK, PLCG1, SCAF11, TIRAP, and TNF was decreased in ACC. This evidence concerns the gene NLRP6 and adrenal cortex carcinoma.