Habibi et al. also found a substantial drop in miR-146a and a rise in IRAK1, NF-κB, and TRAF6 gene mRNAs in the hippocampus part of rats with diabetes, along with enhanced activity of NF-κB and apoptosis levels in this group in comparison with the control group [42]. Here, NFKB1 is linked to diabetes mellitus.