The HWE equilibrium law was followed by the frequency distributions of the following polymorphisms in allergy patients: CYSLTR1 rs320995, GSDMB rs7216389, GPIIIa rs5918, GP1BA rs6065, PEAR1 rs12041331, PAI-1 rs1799762, and TNF-α rs1800629 (p > .05). The gene discussed is SERPINE1; the disease is allergic disease.