HLA-C and Alzheimer disease: Previously, we utilized this cohort to study the Class I HLA genes and found one allele associated with AD, B*53:01, and four alleles (A*01:01, A*02:01, B*07:02 and C*07:02) and six HLA protein residues (HLA-A 9F, HLA-A 97I, HLA-A 152V, HLA-A 156R, HLA-B 163E, and HLA-C 116S) that were associated with protection from AD (Margolis et al., 2021b).