PTPA and cancer: The interaction among CIP2A/p90, PP2A, and c-Myc can hinder the function of PP2A toward c-Myc S62 induction and therefore stabilize c-Myc protein, which represents a potential role of CIP2A/p90 in the promotion of cancer (Pippa and Odero, 2020; Scarpa et al., 2021).