In the ARMS2-HTRA1 locus, rs10490924, rs3793917, and rs11200638 variants have been linked to an increased risk of AMD in Chinese populations (Tian et al., 2012; Zhuang et al., 2014), while rs10490924, rs3750848, rs11200638, and rs2284665 have been associated with a predisposition to AMD in Japanese populations (Yoshida et al., 2007; Akagi-Kurashige et al., 2015). The gene discussed is ARMS2; the disease is age-related macular degeneration.